Jennifer T. Grier, University of South Carolina As someone who studies immune responses to respiratory infections, I’ve watched news of the emerging coronavirus variants with concern. I wondered whether vaccination or previous infection would provide protection against SARS-CoV-2 strains, especially the new, highly transmissible delta variant, which has rapidly spread
Antibody-dependent enhancement (ADE) or “immune enhancement” of viral entry has been observed for many viruses and is a major concern for vaccine development and antibody-based drug therapies. ADE occurs when antibodies from a previous infection or vaccination facilitate viral entry into host cells and enhance viral infection in these cells.
In a new study published in the esteemed journal JAMA researchers at Karolinska Institutet and Karolinska University Hospital have examined the association between a positive SARS-CoV-2 test during pregnancy and complications in mothers and their newborn babies. Almost two out of three pregnant women who tested positive for SARS-CoV-2 were asymptomatic and