CNIC’s study suggests that it may be possible to regulate the number and activity of these macrophages with drugs that modulate the nuclear receptor RXR A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in partnership with researchers at Mount Sinai Hospital in New York, has discovered aRead More →
The first detailed cell atlas of the immune cells and gut bacteria within the human colon has been created by researchers. The study from the Wellcome Sanger Institute and collaborators revealed different immune niches, showing changes in the bacterial microbiome and immune cells throughout the colon. As part of theRead More →
Were you born in an H1N1 year or an H3N2 year? The first type of influenza virus we are exposed to in early childhood dictates our ability to fight the flu for the rest of our lives, according to a new study from a team of infectious disease researchers atRead More →
Most people living with HIV control the virus thanks to antiretroviral therapy (ART). Although this medication is highly effective, the presence of latent viral reservoirs in their bodies means they require lifelong therapy. Studies have demonstrated that immunotherapy combining two anti-HIV antibodies can also suppress HIV, similar to ART. NowRead More →
Certain bacteria can override a defence mechanism of the immune system, so-called programmed cell death, through inhibition of death effector molecules by their outer membranes components. Shigella bacteria, which cause diarrhoea, use lipopolysaccharides (LPS) on their surface to block the effector caspases. Lipopolysaccharides are a component of the bacterial outerRead More →
Immunoglobulins (Ig) or antibodies serve as key detection molecules in the immune system. Antibodies refers to proteins that are produced in B-lymphocytes by the body’s immune system in response to foreign substances or infections, including bacteria or viruses. There are five major classes (isotypes) of immunoglobulins: IgA (immunoglobin A) IgDRead More →
Mycoplasma is an atypical bacterial genus which main characteristic is that naturally lacks cells walls and are the smallest and simplest self-replicating bacteria. The presence of sterols in the plasma membrane helps in regulation of membrane fluidity and protects from osmotic lysis so they don’t need a wall. Some mycoplasma species are pathogenic inRead More →
