Scientists have identified the binding pocket for molecules that can stabilize a key braking mechanism in cancer — opening the door to the development of drugs that target it. A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified theRead More →
Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers. The largest and most comprehensive analysis to date of the link between aspirin and digestive tract cancers, published in theRead More →
UCLA biologists reveal interplay between estrogen and key gene Can women in menopause get the benefits of hormone replacement therapy without the risks? A new UCLA study conducted with mice points in that direction, but additional research is necessary. Women commonly experience hot flashes and weight gain, among other changes,Read More →
An unusual skullcap and thousands of clues have created a southern twist to the story of human ancestors, in research published in Science on 3 April. The rolling hills northwest of Johannesburg are famous for fossils of human-like creatures called hominins. Because of this, the area is known as the Cradle ofRead More →
UC San Diego researchers discover the enzyme SPRK1’s role in reorganizing the paternal genome during the first moments of fertilization — a finding that might help explain infertility cases of unknown cause A sperm enters an egg, an embryo develops and eventually a baby is born. But back up aRead More →
The term “hepatitis” refers to an inflammatory condition of the liver and can be due to different possible causes, including toxic substances, such as alcohol or certain drugs and autoimmune diseases. However, hepatitis viruses are the most common cause of hepatitis around the world. If left untreated, the condition can beRead More →
An investigation in which different Spanish institutions have participated, including the University of Valencia, has shown that the factors that most influence cognitive development in childhood are the formative level of the mother and the social class of the father. The study, on 525 children minors aged 5 and 6Read More →
The first detailed cell atlas of the immune cells and gut bacteria within the human colon has been created by researchers. The study from the Wellcome Sanger Institute and collaborators revealed different immune niches, showing changes in the bacterial microbiome and immune cells throughout the colon. As part of theRead More →
Parabens are used as preservatives in cosmetics. If pregnant women use cosmetics containing parabens that remain on the skin for protracted periods, this may have consequences for their child’s subsequent weight development. This is demonstrated in a study published in the journal Nature Communications by researchers from the Helmholtz Centre for EnvironmentalRead More →
Chromosomal breaks are the most harmful damage for cells. If they are not repaired, they block the duplication and segregation of chromosomes, stop the growth cycle and cause cell death. These breaks appear frequently in tumour cells and are produced spontaneously during the replication of genetic material. To be ableRead More →
