University of Pittsburgh School of Medicine scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause of COVID-19. This antibody component, which is 10 times smaller than a full-sized antibody, has been used to construct a drug–known as Ab8–forRead More →
The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San DiegoRead More →
A COVID-19 outbreak in a refugee settlement will likely overwhelm the available healthcare capacity and infrastructure and spread through nearly the entire settlement population if left unchecked, according to a new study published June 16 in PLOS Medicine by Paul Spiegel of Johns Hopkins University, United States, and colleagues. Forcibly displaced populations,Read More →
Scientists have identified the binding pocket for molecules that can stabilize a key braking mechanism in cancer — opening the door to the development of drugs that target it. A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified theRead More →
Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers. The largest and most comprehensive analysis to date of the link between aspirin and digestive tract cancers, published in theRead More →
ASU researcher explores pests, parasites, diseases on a global scale Countries looking to contain the spread of harmful species and diseases like COVID-19 should work together in multiple hotspots, according to a new model developed by an Arizona State University researcher. Because it would be difficult to completely eliminate theRead More →
Researchers at the University of Iowa and the University of Georgia have developed a vaccine that fully protects mice against a lethal dose of MERS, a close cousin of the SARS-CoV2 coronavirus that causes COVID-19. The vaccine uses a harmless virus to deliver a MERS coronavirus protein into cells toRead More →
University of Pittsburgh School of Medicine scientists today announced a potential vaccine against SARS-CoV-2, the new coronavirus causing the COVID-19 pandemic. When tested in mice, the vaccine, delivered through a fingertip-sized patch, produces antibodies specific to SARS-CoV-2 at quantities thought to be sufficient for neutralizing the virus. The paper appearedRead More →
The next time you eat sashimi, nigiri or other forms of raw fish, consider doing a quick check for worms. A new study led by the University of Washington finds dramatic increases in the abundance of a worm that can be transmitted to humans who eat raw or undercooked seafood.Read More →
As part of continued efforts to respond to the COVID-19 pandemic caused by SARS-CoV-2 virus, researchers report the X-ray crystallography structure of the SARS-CoV-2 main protease – one of the best characterized drug targets among coronaviruses. Insights from their study could drive the design of better inhibitors for the novelRead More →
